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Current Research
Areas
Students currently enrolled at UCSD and interested in a lab
rotation or independent project
I.
Brain computer interfaces (BCIs)
Our interest in BCIs has been to study information maximization by how
information is presented,
developing ways to improve signal detection, and determining how long it takes to learn to develop intentional control of brain rhythms. We are examining factors that can improve learning, such as extensive feedback, a realistic environment, and motivationally-engaging stimuli. We are also interested in whether learning to control brain rhythms affects cognition in general. The basic question is whether subjects who are learning to become more attentive to cognitive states show changes in attention, memory, understanding action, etc (to learn more). .
II.
Mirror neurons, mu rhythms, and autism and observed movement and are thought to contribute to the ability to relate to others (to learn more). We've shown that suppression of EEG oscillations in the mu frequency (8-13Hz) band over prefrontal cortex is correlated with mirror neuron activity. We study this mu wave suppression in a variety of populations to determine how a dysfunctional mirror neuron system may contribute to the pathology in autism, addiction, and other disorders, including a lack of theory of mind. (See news story).
Attention
biases are important mediators of normal,
healthy
motivated behavior that can inform us about
pathological states, such as addiction. Using reaction times (RTs) and event-related potentials (ERPs), we examine the impact of motivatinally-salient cues on normal and abnormal processes when used as spatial cues that frequently predict the location of targets in simple detection tasks. We've shown that such stimuli can bias spatial attention in normal and addicted subjects and that electrophysiological markers exist that index the motivational salience of these cues and their effect on attentional capture. IV. Tinnitus research
Tinnitus—a
persistent “ringing” in the ears that affects approximately 44 million
people
in the U.S. —is
commonly thought to be incurable. One hypothesis suggests that tinnitus activity interferes with the perception of real sounds, causing measurable changes in the patient’s EEG compared to those of normal individuals. Our results suggest a measurable difference between the two groups. We are also developing a sound-based therapy that exposes patients to sounds that mimic their internal noise. Over a short period of time, patients habituate to the sound, and this extends to their tinnitus perception. (See news story). |