Current Research Areas

    Students currently enrolled at UCSD and interested in a lab rotation or independent project
    please contact Dr. Pineda or call 858-534-9754 (lab/office).
  Visit current projects to see
    ongoing experiments.

        I.  Brain computer interfaces (BCIs)
 
      
             Our interest in BCIs has been to study information maximization by how information is presented,
             developing ways to improve signal detection, and determining how long it takes to learn  to develop
             intentional control of brain rhythms.  We are examining factors that can improve learning, such as
             extensive feedback, a realistic environment, and motivationally-engaging stimuli.  We are also interested
             in whether learning to control brain rhythms affects cognition in general.  The basic question is whether
             subjects who are learning to become more attentive to cognitive states show changes in attention,
             memory, understanding action, etc (to learn more).

 .    II.  Mirror neurons, mu rhythms, and autism

             Mirror neurons, originally identified in macaque premotor cortex, become active during self-
             and observed movement and are thought to contribute to the ability to relate to others (to learn more). 
             We've shown that suppression of EEG oscillations in the mu frequency (8-13Hz) band over prefrontal
             cortex is correlated with mirror neuron activity.  We study this mu wave suppression in a variety of
             populations to determine how a dysfunctional mirror neuron system may contribute to the
pathology in
             autism, addiction, and other disorders, including a lack of theory of mind. (See
news story).


    III.  Motivation, attention, and addiction


            Attention biases are important mediators of normal, healthy motivated behavior that can inform us about
            pathological states, such as addiction.  Using reaction times (RTs) and
event-related potentials (ERPs),
            we examine the impact of motivatinally-salient cues on normal and abnormal processes when used as spatial
            cues that frequently predict the location of targets in simple detection tasks.    We've shown that such stimuli
            can bias spatial attention in normal and addicted subjects and that electrophysiological markers exist that index
            the motivational salience of these cues and their effect on attentional capture.  


      IV.  Tinnitus research            

            Tinnitus—a persistent “ringing” in the ears that affects approximately 44 million people in the U.S. —is
            commonly thought to be incurable.  One hypothesis suggests that tinnitus activity interferes with the
            perception
of real sounds, causing measurable changes in the patient’s EEG compared to those of normal
            individuals. 
Our results suggest a measurable difference between the two groups.  We are also developing
            a sound-based
therapy that exposes patients to sounds that mimic their internal noise.  Over a short period
            of time, patients
habituate to the sound, and this extends to their tinnitus perception.  (See news story). 


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